Studies on Sulfenamides. XIII. Reaction of 2-Nitrobenzene-Sulfenanilides with N-Bromosuccinimide.

Solvent free reaction of 1-chloro-2-nitrobenzene with anilines

An efficient solvent free reaction of 1-chloro-2-nitrobenzene with anilines to give N-substituted nitro anilines by nucleophilic aromatic substitution in good to excellent yields has been described. The effect of different salts on the reaction has also been studied.

Further Studies on the Bromodecarboxylation Amino Acids with IV-Bromosuccinimide

In a previous publication from this laboratory, a method was described for the quantitative bromodecarboxylation of amino acids, proteins, and peptides (1). A review of decarboxylating compounds and of the theories pertinent to their mode of action has been presented by Schijnberg and Moubacher (2). The reaction of N-bromosuccinimide with various compounds in organic solvents has received consi...

Chemical modification of ribonucleic acid polymerase with N-bromosuccinimide.

The mechanism of specific interaction between a protein and a nucleic acid is thought to reside partially in the arrangement and types of amino acid present in the protein. Attempts have been made to assign specific roles in this interaction to certain amino acids, for example, tryptophan and tyrosine are thought to be involved in unwinding the double helix of DNA (Brun et al., 1975), and in se...

Flow injection chemiluminescence determination of N-bromosuccinimide and N-chlorosuccinimide.

X-ray studies on phospholipid bilayers. XIII. Interactions with gentamicin.

This study deals with the structural perturbations that the aminoglycoside antibiotic gentamicin (GENT) can produce to phospholipid bilayers. Two multi-bilayer systems, one built-up of dimyristoylphosphatidylcholine (DMPC) and the other of dimyristoylphosphatidylethanolamine (DMPE) were allowed to interact with GENT. The experiments were performed in both a hydrophobic and a hydrophilic medium ...